Glimmer of hope for Alzheimer's treatment.

There’s good and bad with this drug. In CBC today there’s an article warning of severe side effects in over 12% of the very closely monitored folks in the study group.

The drug, lecanemab, was associated with a type of brain swelling in 12.6 per cent of trial patients, a side effect previously seen with similar drugs. Fourteen per cent of patients had microhemorrhages in the brain — a symptom linked to two recent deaths of people receiving lecanemab in a follow-on study — and five patients suffered macrohemorrhages.
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https://www.cbc.ca/news/health/alzheimers-lecanemab-trial-results-1.6668945
 
Jules said:
There’s good and bad with this drug. In CBC today there’s an article warning of severe side effects in over 12% of the very closely monitored folks in the study group.
Click to expand...
You are right of course, and it's benefits are limited, only reducing the rate of decline into dementia by about 27 percent. If anything useful comes from this it is likely years away.

However there does seem to be some hope that the mechanism of slowing, and maybe stopping it are being better understood.
 

https://www.abc.net.au/news/2022-08... images published by scientists years earlier.

This discovery has set things back. Its rare for these studies to be fraudulent but this one got through and millions or more dollars had been spent before it was uncovered.


I tend to follow Dr Maria Gorilla on this subject. I couldn't find it to share but she did a years long study in a retirement village in California. I think it was on PBS, not sure.
It was fascinating.
Most residents with amyloid plaque got dementia, some with plaque did not. Some got dementia but had no plaque. There were few common denominators.
 

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