Thanks @hollydolly for the link, the kind of technical medical sites I visited most during the pandemic. Easily the best summary description of these immensely complex machine-like ligand chemical keying cell processes I've watched now that 2+ years of research has built up. From the earliest months, this is what I, someone with just basic cell process knowledge has been relating and posting online. That the reason some people are asymptomatic or immune is likely due to previous earlier related coronavirus infections that primed our immune T-cell systems.
As a child growing up in schools in Northern California, we were stricken by a lot of respiratory diseases. In our region the ones that have dominantly come down with COVID-19 especially those that died, have been immigrants both from other states or countries that may not have been exposed to the same diseases. Though national and state media has continually bent over backwards to suppress that narrative as well as access to data for usual PC reasons. The vast majority of adults in California are not natives and instead have moved here from other states or countries. I've had 3 Pfizer shots, worn masks earlier and during last year been in many crowded public places without a mask.
We speculate that high affinity of HLB-*15:01 for binding WTAGAAYY or another unknown viral petide confers strong CD
An alternative explanation for our rsults is that HLB-*15:01carriers previously infected by other common coronavires have pre-existing cross-reactive T-cells with high affinity for specific epitope conferred by this HLA molecule... A subset of T cells primed against seasonal coronaviruses cross reacts with SARS-CoV-2 and may contribute to clinical protectionn, particularly early in life...