Melange, often referred to as "the spice", is the fictional
psychedelic drug central to the
Dune series of
science fiction novels by Frank Herbert and derivative works.
In the series, the most essential and valuable commodity in the universe is melange, a drug that gives the user a longer life span, greater vitality, and heightened awareness. In some humans, the spice can also unlock prescience, a form of precognition based in genetics but made possible by use of the drug in larger dosages. Among other functions, prescience makes safe and accurate interstellar travel possible.