I had several ideas for new businesses when I was at the height of my career but was drawn in by the thought of the security my career provided, so I never followed through with them. I did, however, leave a secure, well-paying job of 15 years to go to a tech-savvy "start up" company in 2000. It was a miserable time in my life, but it eventually got me to a better place when a good friend asked me to go to work for her at an established company. I did, and I stayed there for 20 years before retiring.
Back in 2006, I had the idea of researching new places to live after 18 years in South Florida. We were not happy living there (hurricanes, traffic, rude people). We ended up moving to Dallas because it made financial sense and I was willing to make the leap. My company kept me, so I worked from home for 14 years. We still love our quality of life and have never looked back. We also relocated my mother from South Florida to Dallas. I bought her place in her 55+ community pre-construction, picked out her location and the finishes in her home. She always said it was the favorite place she'd ever lived.
So, I'm all for change if it's for the better. "No guts, no glory".