Alarm over 200% explosion in young women and girls getting pancreatic cancer

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A 'frightening' explosion of young women developing one of the deadliest cancers has baffled experts.

Rates of pancreatic cancer have soared by up to 200 per cent in women under the age of 25 since the 1990s.

Overall, incidences of the disease — which has a five-year survival rate of just 5 per cent — have increased by around 17 per cent over the same time-span, with soaring obesity rates suspected to be behind the trend.

Yet oncologists cannot explain the particular surge in young women, with no such spike noted in men of the same age.

​

Professor Karol Sikora, a world-renowned oncologist with over 40 years' experience,said there are theories it has to do with the modern diet.


But so far, he added, researchers have 'no idea' of the cause behind the 'frightening' trend, especially in younger woman.

'It is probably something to do with dietary change over the last 20 years,' he said.

'Fortunately pancreatic cancer is rare in the young but it is a bit worrying. It shows that we just don't have all the answers.'
He added that Britain wasn't alone in this trend, with studies from the US indicating similar increases in the disease across the Atlantic and further research was needed to uncover the cause.
Nicola Smith, senior health information manager at Cancer Research UK, also said more research was needed to unpick why pancreatic cancer rates in the UK were increasing.

Other known risk factors for the disease include smoking and obesity.

Figures from Cancer Research UK (CRUK) shows pancreatic cancer incidence rates have risen 17 per cent since the early 90s.

It now means that about 17 people out of every 100,000 will get the disease in one calendar year.

This is up from 14 people per year some 30 years ago.

Pancreatic cancer incidence rates in young women, those who are children and up to the age of 24, have exploded by 208 per cent over the same period, MailOnline analysis revealed.

Rates of the disease in women aged 25 to 49 also increased by 34 per cent, nearly double the rate of the general population.


I don't think it's as much to do with food as it is to do with alcohol...

There has been little or no rise in young men getting this disease, yet the rise in females has risen hugely... since the 90's... and I believe it's the rise in drinking alcohol I see as many women if not more, out on the weekends drinking drink for drink with the guys until well into the early hours.. and several nights in a row..... and women think it's perfectly ok to be drinking at home during the day with a bottle of wine.. as their companion...

There's also been a big rise in women being stopped for drinking and driving, particularly in the day time..
 

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That's an interesting theory. I hear guys talking about craft beers and such now and then but little about regularly going out to drink or even guzzling at home. I suppose a cultural shift might be at work.
 
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I'm betting it's the cheap plastic bottles of water. Remember all things processed have harmful stuff in them.
Most everything the girls drink comes in a plastic bottle or Cup at the Moto Mart.. WE JUST NATURALLY BELIEVE THAT DRINKING FROM A BOTTLE IS SO MUCH MORE HEALTHY THEN FROM A GLASS. NOT SO.

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These environmental effects should make us switch to reusable water bottles and avoid drinking water in plastic bottles. Many health concerns arise due to drinking water in plastic bottles. Below mentioned pointers will give you an insight into the process of plastic bottles degrading the quality of water and ultimately causing adverse effects on our health.


ps://www.bing.com/search?q=Toxins+contained+in+plastic+bottles&form=ANNTH1&refig=43b163f65e7d48c5a3b7e27791143e11&pc=U531
 
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dilettante said:
That's an interesting theory. I hear guys talking about craft beers and such now and then but little about regularly going out to drink or even guzzling at home. I suppose a cultural shift might be at work.
Click to expand...

Young folk today don't tend to go out to drink and get blitzed. instead they drink BEFORE going out, which has the same result but costs less to do. Hence a lot of pubs and nightclubs are closing these days.

Smoking is, apparently, the leading cause. Not sure how that relates to the current trend of vaping though.

I thought the Lancet article was interesting:

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00039-0/fulltext

"Previous analysis of data from other sources has also found that increases in the incidence of pancreatic cancer are largest in the youngest age groups. In one study, the average annual percentage change (AAPC) in pancreatic cancer incidence between 1995 and 2014 was 0·77% in those aged 45–49 years, but 4·34% in those aged 25–29 years. These trends seemingly mirror the rising incidence of some other early-onset digestive cancers, including colorectal and gallbladder malignancies.

The new study not only affirms these observations, but also reveals sex and race differences in these changes. The AAPC in pancreatic cancer incidence between 2001 and 2018 in individuals younger than 55 years was 1·29%, and was substantially higher in women (2·36%) than in men (0·62%), with incidence increases in women versus men also more rapid in Black people than in White people. In the youngest age group assessed, those aged 15–34 years, the AAPC was even higher, at 6·45% in women and 2·97% in men. By contrast, for those aged 55 years or older, the AAPC was 1·11%, with no difference between men and women.

It is important to consider these changes in context. During the study period, 454 611 people were diagnosed with pancreatic cancer, of whom 53 051 were younger than 55 years and only 2452 were aged 15–34 years. The overall incidence of early-onset pancreatic cancer also remained substantially higher in men (13·95 per 100 000) than in women (10·69 per 100 000), and men had a higher risk than women in all but the 15–34 years age group.
Nonetheless, these findings raise questions. Why is the overall incidence of pancreatic cancer increasing? What factors might be driving sex and race differences in these trends? Increases in the number of pancreatic cancers in young women have been noted in other countries, including the UK, where incidence rates between 1993 and 2018 increased by 208% in females aged 0–24 years and by 34% in those aged 25–49 years."
 
Most advertisements of the plastic water bottles show that the water is taken straight from mountains to show that their water is of esteem quality than regular tap water.

However, taking water from springs is rare. The water in these bottles is taken from similar sources to your state’s water supply. The only difference is the branding of the bottle.

Is the water filtered?
Many water bottle companies ignore the basic water filtration process that makes the water safe for consumption while manufacturing these bottles
 
HAVING A REFRESHMENT CONTAINED IN A PLASTIC BOTTLE OR CUP WHEREVER WE GO IS JUST LIKE HAVING THE PHONE ON THE DASH OF THE CAR. ITS ACCEPTED BEHAVIOIR. IF ITS MANUFACTURED ITS BAD FOR YOU. EVEN WINE HAS CHEMICALS IN IT TO KEEP IT FRESH. SOME GET DEATHLY ILL BECAUSE THEY ARE ALLERGIC TO THE CHEMICALS MENT TO KEEP THE WINE FRESH. JUST READ THE LABEL, OF COURSE YOU NEED A MAGNIFYING GLASS. THE HUMAN IS CONDITIONED TO ACCEPT THE RISK TO JUST HAVE THE LIFESTYLES.

STILL, WE ARE MORE APT TO BE TAKEN OUT ON THE EXPRESSWAY.
 
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Plastic bottle are usually advertised as BPA free.. and in any case.. as many young men, and older adults drink out of plastic bottles as young women... and there's only a rise in Pancreatic cancer in the young under the age of 25...
 
papa tiger said:
Most advertisements of the plastic water bottles show that the water is taken straight from mountains to show that their water is of esteem quality than regular tap water.

However, taking water from springs is rare. The water in these bottles is taken from similar sources to your state’s water supply. The only difference is the branding of the bottle.

Is the water filtered?
Many water bottle companies ignore the basic water filtration process that makes the water safe for consumption while manufacturing these bottles
Click to expand...

To be honest, if the source is plastic bottles, wouldn't our generation have been affected also? I mean, we were around when they switched from glass to plastic, and we knew a whole lot less about things leaching into the beverage back then.

Mind you, I saw a story about plastics and food the other day - it's truly shocking. Just about everything we're eating these days has microscopic levels of plastic in it.

But then, I think it's important to remember and accept that there is unlikely to be one, and only one reason for such things. It's a complex world, and our interactions with it are varied. Different combinations of circumstances combine to make results. The Lancet article says that research into this type of cancer is small, which leaves holes in the data.
 
Women around the home have a tendency to work with pesticides and Chemicals without the benefit of proper ppe.
  • Working with pesticides and chemicals causes Pancreatic Cancer.

PFAS is short for per- and polyfluoroalkyl substances, a chemical class that includes approximately 5,000 compounds that have been linked to cancer and learning delays in children. Used in numerous consumer products, the compounds are known as “forever chemicals” because the bonds that hold PFAS together don’t break down easily in the environment.
New Study Finds PFAS in Bottled Water - Consumer Reports

Are the toxins in plastic bottles forever chemicals - Bing It's not only drinking bottles, but all foods stored in plastic. Most all are.

It's the "forever chemicals" that are in our blood ! Farm wives had large health concerns %'s due to well water.
The farm men usually drank the most water from the High Volume well, the same as the livestock.

If you check out the Water treatment changeovers you also see the Mains 100's of miles of them, are being replaced in the Major Cities.

Most likely the best is Add Some pure honey to the Tea or Coffee instead of Sugar. The Question to answer is Honey Bee's ? &
Of Course The Honey Comes in a Plastic Squeeze Bottle !

Forever Chemicals in Our Environment: What They Are and How to Avoid Them
 
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If it is an increase in young women it would seem it should be related to something new that is done by young women. I'm not sure if drinking is all that new, and smoking rates have presumably gone down. Maybe young women are becoming more obese, but maybe there are some new bad contaminants in makeup or birth control?
 
Nathan said:
Obesity rates have skyrocketed, even with young children as the Fast Food culture has become entrenched. The rate of pancreatic cancer incidence increase is no huge surprise.
Click to expand...
..again everyone has become much fatter.. so if that was the reason then why are only under 25 females affected..

@HoneyNut could potentially be pointing in the right direction with birth control..however again.. millions of women over 25 take birth control, and their incidences have not increased...

It's a fascinating subject I hope they don't long in finding the cause..
 
HoneyNut said:
If it is an increase in young women it would seem it should be related to something new that is done by young women. I'm not sure if drinking is all that new, and smoking rates have presumably gone down. Maybe young women are becoming more obese, but maybe there are some new bad contaminants in makeup or birth control?
Click to expand...

Birth control? Why birth control? Birth control has been around for a long time.

Nathan said:
Obesity rates have skyrocketed, even with young children as the Fast Food culture has become entrenched. The rate of pancreatic cancer incidence increase is no huge surprise.
Click to expand...

Which suggests that it's obesity causing the issue, yet smoking is still recognized as the leading cause.
 
Nathan said:
I didn't know that, seems odd statistically as smoking has been on the decline.
Click to expand...

Well, "vaping" gets a free pass, but there's not been all that much research on it. I don't know what research would show......... but then again, it simply may not be related to the increase.

We can't ignore increased testing............
 
I don't believe obesity is the problem.. because there's are just as many of not more people over 25 who are super obese and the incidences amongst that age group has not risen...

My money is still on the huge increase in under 25 female drinkers...
 
VaughanJB said:
Young folk today don't tend to go out to drink and get blitzed. instead they drink BEFORE going out, which has the same result but costs less to do. Hence a lot of pubs and nightclubs are closing these days.

Smoking is, apparently, the leading cause. Not sure how that relates to the current trend of vaping though.

I thought the Lancet article was interesting:

https://www.thelancet.com/journals/langas/article/PIIS2468-1253(23)00039-0/fulltext

"Previous analysis of data from other sources has also found that increases in the incidence of pancreatic cancer are largest in the youngest age groups. In one study, the average annual percentage change (AAPC) in pancreatic cancer incidence between 1995 and 2014 was 0·77% in those aged 45–49 years, but 4·34% in those aged 25–29 years. These trends seemingly mirror the rising incidence of some other early-onset digestive cancers, including colorectal and gallbladder malignancies.

The new study not only affirms these observations, but also reveals sex and race differences in these changes. The AAPC in pancreatic cancer incidence between 2001 and 2018 in individuals younger than 55 years was 1·29%, and was substantially higher in women (2·36%) than in men (0·62%), with incidence increases in women versus men also more rapid in Black people than in White people. In the youngest age group assessed, those aged 15–34 years, the AAPC was even higher, at 6·45% in women and 2·97% in men. By contrast, for those aged 55 years or older, the AAPC was 1·11%, with no difference between men and women.

It is important to consider these changes in context. During the study period, 454 611 people were diagnosed with pancreatic cancer, of whom 53 051 were younger than 55 years and only 2452 were aged 15–34 years. The overall incidence of early-onset pancreatic cancer also remained substantially higher in men (13·95 per 100 000) than in women (10·69 per 100 000), and men had a higher risk than women in all but the 15–34 years age group.
Nonetheless, these findings raise questions. Why is the overall incidence of pancreatic cancer increasing? What factors might be driving sex and race differences in these trends? Increases in the number of pancreatic cancers in young women have been noted in other countries, including the UK, where incidence rates between 1993 and 2018 increased by 208% in females aged 0–24 years and by 34% in those aged 25–49 years."
Click to expand...
Why do they publish articles in unreadable colors?
 
very few people smoke in the UK...and these worrying fining among the under 25 female population and significant rise in 25-49 year old females.. is not jut the UK...studies from the US indicating similar increases in the disease across the Atlantic baffling Cancer specialists there.
 
I recall on my two trips to the UK (England and Scotland) that drinking in pubs is legend. Even the females who usually can’t hold their liquor as well as larger males drink heartily. I find that sad. A drunken female is not very attractive.

And, because I watch all those British shows on public TV and occasionally BritBox, I know that just about anything that happens in the UK is a reason to go to the local pub and have several pints. Wife have a baby, drink a few beers. The post arrived early today, have a few beers. A murderer has killed the favorite to win the cake decorating contest, hit the pub and down more beer. Ladies get together to knit socks, open a few bottles of wine and finish them off. Charging the EV while driving to Glasgow, walk over the local pub and enjoy a few more pints. ;)
 
Devi said:
I use the regular setting, and the text shows as light yellow without much contrast against the white background.
Click to expand...

Yeah, I can see how that would be am issue. I tend to turn every site I use black, makes it a little easier on these old eyes. That said, a couple site members use dark blue text sometimes, and I've no chance of reading those. Mind, just highlight the text to see it clearly. ;)
 
My pancreatic cancer specialist (I have a very small lesion but not cancer) told me that one of the reasons more cases are being diagnosed is the increased use of CT scans and MRI’s when looking for other things. By the time symptoms present it’s too late. Find it early before it gets large, it’s treatable or in some cases monitored for changes. I go for a MRI once a year.
 

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