AnnieA
Well-known Member
- Location
- Down South
This is the most sensible way in which to assure safety since recent Israeli data shows a significantly higher protection rate from prior "natural" infection than vaccine conferred. Recovered, unvaccinated people would substitute an antibody titer instead of a vaccination record. Most people won't after going to the trouble to get vaccinated, but it's also a good idea for the elderly, obese and those with inflammatory medical conditions to have antibodies tested post vaccination since those groups are high risk for poor antibody response to vaccines.
Ideally, all would be antibody titer based and antibodies checked every 3-6 months but I can see where that would be a burden on several levels. It would be ideal though, since the Israeli study showed on dose of vaccine boosted waning natural immunity. It would also show when vaccinated subjects with no history of infection need a booster.
References:
Obesity and vaccines
Israeli study--new data awaiting peer review
https://www.medrxiv.org/content/10.1101/2021.08.24.21262415v1.full.pdf
Excerpt:
(naïve vaccinees are vaccinated subjects with no history of infection)
SARS-CoV-2-naïve vaccinees had a 13.06-fold...increased risk for breakthrough infection with the Delta variant compared to those previously infected, when the first event (infection or vaccination) occurred during January and February of 2021. The increased risk was significant (P<0.001) for symptomatic disease as well. When allowing the infection to occur at any time before vaccination (from March 2020 to February 2021), evidence of waning natural immunity was demonstrated, though SARS-CoV-2 naïve vaccinees had a 5.96-fold...increased risk for breakthrough infection and a 7.13-fold (95% CI, 5.51 to 9.21) increased risk for symptomatic disease. SARS-CoV-2-naïve vaccinees were also at a greater risk for COVID-19-related-hospitalizations compared to those that were previously infected.
...The advantageous protection afforded by natural immunity that this analysis demonstrates could be explained by the more extensive immune response to the SARS-CoV-2 proteins than that generated by the anti-spike protein immune activation
conferred by the vaccine...
Ideally, all would be antibody titer based and antibodies checked every 3-6 months but I can see where that would be a burden on several levels. It would be ideal though, since the Israeli study showed on dose of vaccine boosted waning natural immunity. It would also show when vaccinated subjects with no history of infection need a booster.
References:
Obesity and vaccines
Israeli study--new data awaiting peer review
https://www.medrxiv.org/content/10.1101/2021.08.24.21262415v1.full.pdf
Excerpt:
(naïve vaccinees are vaccinated subjects with no history of infection)
SARS-CoV-2-naïve vaccinees had a 13.06-fold...increased risk for breakthrough infection with the Delta variant compared to those previously infected, when the first event (infection or vaccination) occurred during January and February of 2021. The increased risk was significant (P<0.001) for symptomatic disease as well. When allowing the infection to occur at any time before vaccination (from March 2020 to February 2021), evidence of waning natural immunity was demonstrated, though SARS-CoV-2 naïve vaccinees had a 5.96-fold...increased risk for breakthrough infection and a 7.13-fold (95% CI, 5.51 to 9.21) increased risk for symptomatic disease. SARS-CoV-2-naïve vaccinees were also at a greater risk for COVID-19-related-hospitalizations compared to those that were previously infected.
...The advantageous protection afforded by natural immunity that this analysis demonstrates could be explained by the more extensive immune response to the SARS-CoV-2 proteins than that generated by the anti-spike protein immune activation
conferred by the vaccine...