Michael Eades: New Hypothesis of Obesity

As we are dealing with obesity, health problems, nutrition, and healthy foods it seems like a no brainer to cut back on highly processed food. Our bodies do not metabolize this non-food stuff. So if you stayaway from it and eat nutritionally it will definitely help. If you you want to really try the low carb, high meat/fat diet/Keto fasting for about 12 hours will change your gut metabolism to start burning your energy with ketosis, just fooling around with this and that is not going to do anything.

Recent studies published link highly processed food to colorectal cancer, as well.

https://now.tufts.edu/2022/08/31/new-study-links-ultra-processed-foods-and-colorectal-cancer-men
 

The science is a bit complicated, but the recommendations are very simple.
The video was interesting. I'm not sure I am totally on board with his idea of cutting out linoleic acid, I thought that was necessary for skin, eyes, and brain - but presumably he only means cut out the excess of it that we get with some of the vegetable oils.

I do feel agreement with the study he was showing where kids (I think it was teens?) were satisfied with a lot fewer calories of baked (or was it boiled?) potatoes with butter versus how many more calories of french fries they ate before feeling equally satisfied. I know I can eat enormous amounts of french fries, they are just so yummy I want more and more.

But simple answers are dubious. I think an equally valid presentation could be done with graphs of how we have gotten fatter as we have gotten less sleep over the past decades.

I watched this interesting YouTube last week (while waiting for a dryer, why do people not return promptly for their clothes?!) about how different people react differently to types of foods, so that there is no single perfect diet for everyone. They monitored blood glucose of people eating different diets and a food that would cause some people to get a blood sugar spike would not cause a spike in other people. If I wasn't so scared of being pricked by a needle I think I would like to monitor my glucose reaction to different foods.

 
Thanks to modern technology, it's easier to determine if you're overweight. We have scales with computerized voices that say your weight, instead of a display.
If it says a number, you're fine.
If it says "One at a time, please," you're overweight.
 

We were on the road the other night and wound up eating in a Cracker Barrel. For a variety of reasons, there were no other options.

The caloric content of the foods was very clearly labeled. Nevertheless, the tables were full of very fat people shoveling down fried chicken, fried catfish, mashed potatoes and gravy, Coke and apple pie with ice cream.

So I'm not sure people are eating "heart healthy". Rather I think people say they are eating "heart healthy" then eating what they please.
Yep, places like Cracker Barrel help create all those very fat people, the only items they serve that are "heart healthy" are water and paper napkins.
 
I'll ask a simple question to you folks who seem convinced that you know better. We are currently in the midst of a world-wide pandemic of metabolic diseases: CVD, diabetes, obesity and many other related chronic diseases. How does this come about when we're eating the 'low fat high carb' and 'heart healthy' diet recommended by our dietary and nutritional betters.
Knowledgeable dieticians and nutritionists will give valuable guidance, it is the profiteers and charlatans that will make money off of the followers health.
 
About weight management: I think most of us that grew up in the 60s-70s were familiar with counting calories, and as a result have a poor or incomplete understanding of carbs and their health impact. I still have to refresh on carbs, here is an article on Carbs vs. Calories.
 
So I'm not sure people are eating "heart healthy". Rather I think people say they are eating "heart healthy" then eating what they please.
In his presentation Eades displays several graphs he made to show the increase/decrease in consumption of various foods beginning 1971. The graphs clearly indicate an overall increase in carbs and overall decrease in fat consumption while overall protein remained about the same. He also displays graphs of the consumption of various different fats during the same period. Per our 'heart healthy' dietary guidelines sat fat decreases but what is surprising is that PUFA intake increases significantly to become the dominant fat consumed. This due almost entirely to increased consumption of industrial seed oils: canola, soya, corn, etc. Eades also compares the increase in PUFA consumption to the increase in obesity over the same period of time and they overlap almost exactly.

Eades asked the simply question 'Why did the obesity epidemic increase in lockstep with industrial seed oil consumption?' Was it just random correlation - or causation? Which led to his discovery - with the help of Petro Dobromylskyj at Hiperlipid - and the very detailed discussion of proton transport in the mitochondria.

It's an hypothesis that I think worth investigation.
 
Where does the topic of exercise fit into this thread? I can try all the fad diets I want, but if I don't exercise I can only see minimal benefits.

We eat healthy, but I ate a Quarter Pounder with Cheese from McDonald's yesterday because I occasionally crave red meat and was ravenous after working out. I don't think it will kill me, but sitting on my ass all day surely will.
 
I have an hypothesis. The thyroid is the master rheostat that controls your metabolism. Myriad metabolic processes go on all the time. Most have their own internal regulators - for example: glucose/insulin. Overall, the thyroid controls how 'fast' (aka catabolic) or how 'slow' (aka anabolic) the metabolism operates. There is a range of 'normal' activity from relatively more catabolic at one end to relatively more anabolic at the other.

For example, again, my dad was a healthy, vigorous young man until hyperthoidism developed. His metabolism shifted so far into the catabolic state that he could not eat fast enough to prevent literal starvation. He ate voraciously while slowly starving to death. After his thyroid was nuked he experienced the exact opposite. Very little of what he consumed was utilized for energy, most was stored - as fat, not healthy lean mass like muscle and bone.

My dad was not a masochist nor suicidal. When hyper he did not want to starve - he wanted to live and be healthy. When hypo he did not want to be obese or diabetic. He did not do this to himself by eating at Cracker Barrel or Chucky Cheese. He wanted to live a normal life not carry around 2-300 pounds of flab everywhere, every day. He did not want to take diabetes medication for half his life. He did not want to have his first heart attack at the age of 63. He did not want to have 4 bypass surgeries. He was eating the standard North American diet and a lot less of it than most. And it was the worst diet he could have been prescribed. He really believed that calories in and calories out worked and never understood why it didn't for him.

Take myself as a second example. I did not get hyperthyroid, but I inherited the next best thing - my healthy thyroid ran my metabolism at the catabolic end of the 'normal range'. All my life I ate the standard North American diet yet I maintained healthy overall weight and body fat composition. That included decades eating seed oils and margarine. That included 30 years brewing my own beer and drinking half a liter or more daily. At the catabolic end of the normal range, my metabolism was oriented to utilize energy, not store it. I think as a result I did not suffer the common consequences - not obese, not diabetic, no CVD or any related metabolic disease.

My dad was an extreme example of folks at the anabolic end of that range. Metabolism at the anabolic end of the range is oriented to store energy, not use it. A diet like the standard North American keeps insulin elevated virtually 24/7/365. The job of insulin is to remove glucose from the bloodstream. Some of which will get moved into muscle cells where it will be used as energy or stored as glycogen, but most will get stored in fat cells where it gets converted to fat. The liver will also make additional fat to use up whatever excess glucose is floating around. So combine a high carb - insulin on 24/7 mode - high PUFAs - that interfere with mitochondria doing their job efficiently - with a metabolism drifting along at the anabolic end of the range. That's a recipe for obesity. And a host of related metabolic disorder.

I think human metabolism evolved to maintain homeostasis. A healthy metabolism lets us know when it needs energy and when it's got enough, when we require additional necessary nutrients and when we don't. A healthy body in overall energy balance is the result of a healthy metabolism - so I think the whole 'energy balance' obesity hypothesis is ass backwards. I think if this were not true, our species and its predecessor species would have gone extinct long ago. We would not have lasted during millions of years of the paleolithic if obesity, diabetes and CVD were common as they are now. And I think we won't last much longer unless we address these problems intelligently. I think the adoption of agriculture after the onset of the Holocene and the gradual shift towards higher and higher carb eating and away from animal eating was the start of a human disaster - made worse by an order of magnitude now by consumption of industrial seed oils. I think it's an extinction level event. And should be addressed as such.

Just my opinions, of course. 👍
 
Stay to the outside lanes at the supermarket. In other words, eat the fresh foods and Whole Foods rather than all the boxed up and packaged processed foods
Since there are more overweight people shopping, you'll have to stay to the outside lanes; there ain't much room in the middle.
 
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Saw a funny British TV Comedy Show years ago. The name of the show escapes me.

The overweight female woman laments to her sister, "Inside of me there's a thin person just waiting to get out!"

Her sister looks her up and down and says...

"Are you sure there's just the one?"

:D
 
I've always been the kind of guy who can eat whatever he wants...
... and I just get really, really fat.

*** rimshot ***
 
You know you're overweight when you're at the beach, trying to get a tan & people keep pushing you into the water.
 
I remember losing a lot of weight when I was doing a lot of illegal drugs. I also lost a lot of weight when a flare up of GERD prevented me from eating much of anything. My advice is if you want to lose weight fast, be stupid and get sick.
 
In his presentation Eades displays several graphs he made to show the increase/decrease in consumption of various foods beginning 1971. The graphs clearly indicate an overall increase in carbs and overall decrease in fat consumption while overall protein remained about the same. He also displays graphs of the consumption of various different fats during the same period. Per our 'heart healthy' dietary guidelines sat fat decreases but what is surprising is that PUFA intake increases significantly to become the dominant fat consumed. This due almost entirely to increased consumption of industrial seed oils: canola, soya, corn, etc. Eades also compares the increase in PUFA consumption to the increase in obesity over the same period of time and they overlap almost exactly.

Eades asked the simply question 'Why did the obesity epidemic increase in lockstep with industrial seed oil consumption?' Was it just random correlation - or causation? Which led to his discovery - with the help of Petro Dobromylskyj at Hiperlipid - and the very detailed discussion of proton transport in the mitochondria.

It's an hypothesis that I think worth investigation.

Very interesting. You seem to have a scientific background, and you can focus on the details to a much greater extent than I can.

We switched to butter and/or olive oil years ago. We have the same bottle of Wesson Oil that's been sitting in our cupboard since then.
 
Where does the topic of exercise fit into this thread?

... but sitting on my ass all day surely will.

Excellent question! And I will respond using myself as an example.

As a youth and young man (high school and university) I was a competitive athlete, middle distance running. I continued afterwards being physically active although not at a competitive level. There was no period during my entire adult life when I felt the necessity to 'exercise' simply because I was physically active all the time. I walked. I hiked. I cycled. I was never a 'couch potato' and never felt like I had to 'go to the gym' to workout or adopt an 'exercise program'.

But the big question is 'why'. I think the answer is my thyroid hypothesis described above. I was blessed with a healthy metabolism and as a consequence had a healthy body and a healthy lifestyle. At the catabolic end of the 'normal' metabolic range of activity I was naturally inclined to utilize energy rather than store it. As a result I did things that used energy and thought nothing of it. I did not have to 'think about' the topic of exercise. I simply 'did it'.
 
Where does the topic of exercise fit into this thread? I can try all the fad diets I want, but if I don't exercise I can only see minimal benefits.

We eat healthy, but I ate a Quarter Pounder with Cheese from McDonald's yesterday because I occasionally crave red meat and was ravenous after working out. I don't think it will kill me, but sitting on my ass all day surely will.
On a different forum several years ago, someone mentioned to me that weight loss is like 85% what-goes-in-the-piehole...and maybe 15% exercise. Being older means moderate exercise, extreme cardio, weight training and aerobics will likely cause missed workouts due to overly sore muscles and joints. I have osteoarthritis so I avoid heavier weights, instead doing more repetitions with lighter weights. I practice
Taichi, Qigong and Yoga for gentle motion and stretching, feel-good stuff. ;)
 


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