The FDA is currently studying psilocybin therapy aimed at treating chronic low back pain

Murrmurr

Murrmurr

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The FDA is currently reviewing studies for psilocybin therapy aimed at treating chronic low back pain, with clinical trials being conducted to evaluate its effectiveness. This could represent a significant step in the use of psychedelics for pain management.

It is expected psychedelics, MDMA and LSD will also prove effective in the treatment of certain mental health issues, including PTSD, severe depression, and suicidal ideation. U.S. veterans have reported benefiting from these drugs after traveling to clinics in Mexico that administer it.
 
Rakaia said:
If this happens will there be retrospective pardons for the previously convicted?
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It's possible, but....

When marijuana was first decriminalized and later legalized in various US states, prison doors did not swing open for anyone convicted of sales or possession until state and federal legislators created new laws that made it legal to release them.

Federal laws must be proposed, debated, then voted on by the congressional House that proposed it before being sent to the other House to be argued, possibly changed, and then voted on. If changed, it must go back to the House that originally proposed it for more argument, possible changes, and a new vote.

State laws also involve several steps. After a bill is introduced, it is often assigned to a committee for study, then debated and voted on in both legislative chambers before being sent to the state governor for a signature.

As you can imagine, both processes can sometimes take years. And while most state and federal lawmakers wanted to get people convicted of marijuana violations released from decades-long state and federal prison terms, they had to be especially careful with the wording of the new laws, particularly the retroactive ones, to ensure they could not be exploited by defense attorneys whose clients were behind bars far more serious and violent crimes. That in itself caused lengthy debates and further delays.
 
Just guessing and thinking like a cop, but I can imagine there will either be a roadside test or a blood draw, if caught driving erratically or involved in an accident. If this would come about, it’s likely there will be a code in the Pennsylvania Vehicle Code Book and as such, I would also expect some type of punishment would be handed out as issued by the Commonwealth General Assembly.

Because psilocybin has proven to have the potential to alter one’s thinking and reasoning, it may be considered a controlled substance, if it hasn’t already. Just what we need. More spudnuts on the highways. “Gee, I think I will take my psilocybin and then go for a ride down the PCH.” (A little humor.)

All speculation on my part.
 
911 said:
Just guessing and thinking like a cop, but I can imagine there will either be a roadside test or a blood draw, if caught driving erratically or involved in an accident. If this would come about, it’s likely there will be a code in the Pennsylvania Vehicle Code Book and as such, I would also expect some type of punishment would be handed out as issued by the Commonwealth General Assembly.

Because psilocybin has proven to have the potential to alter one’s thinking and reasoning, it may be considered a controlled substance, if it hasn’t already. Just what we need. More spudnuts on the highways. “Gee, I think I will take my psilocybin and then go for a ride down the PCH.” (A little humor.)

All speculation on my part.
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It will be considered a controlled substance, according to the FDA.

In conjunction with research, some universities and general laboratories will be adjusting/rearranging its molecular structure for the purposes of medical treatment for both physical and mental health problems, and I imagine Big Pharma will also. I'm sure this will include reducing the hallucinogenic properties, but I don't doubt law enforcement will have to come up with a low-range for impaired driver, right?

That will probably be FDA recommended. I believe that's the case with Rx opioids. I take a prescribed opioid, but I can be charged with a DUI if I'm involved in a fender-bender or something and test above whatever the Calif limit is. Doesn't matter that it's prescribed.

I bet the only way to measure that will be a blood test...that presents a problem.
 
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Murrmurr said:
It will be considered a controlled substance, according to the FDA.

In conjunction with research, some universities and general laboratories will be adjusting/rearranging its molecular structure for the purposes of medical treatment for both physical and mental health problems, and I imagine Big Pharma will also. I'm sure this will include reducing the hallucinogenic properties, but I don't doubt law enforcement will have to come up with a low-range for impaired driver, right?

That will probably be FDA recommended. I believe that's the case with Rx opioids. I take a prescribed opioid, but I can be charged with a DUI if I'm involved in a fender-bender or something and test above whatever the Calif limit is. Doesn't matter that it's prescribed.

I bet the only way to measure that will be a blood test...that presents a problem.
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I'd like to know how (and/or if) they intend to accomplish this..
 
Sunkist said:
I'd like to know how (and/or if) they intend to accomplish this..
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Under a microscope.

Seriously, molecular engineering. I know of only 2 methods, rearranging the molecular structure (of psilocybin in this case) to create derivatives, and/or introducing molecules from other known medicinal chemicals.

That's basically how we got medicinal marijuana in various strengths and with various properties. Researchers hope to create at least 3 types of psilocybin medications, for pain, for severe depression and related disorders, and as a treatment for severe drug addiction. They talked about its potential to cure opioid addiction in particular.

I'd post the press-conference video or link, but it took place in the White House Oval Office and several politicians spoke, so it would very likely violate our no politics rule.
 
There are research projects going on in four or five cities in the U.S., aimed at establishing psilocybin's usefulness in treating emotional issues, such as PTSD and depression. England has pursued this, possibly for longer than the projects n the U.S. For several years now, Canada has had a cross-country project for psilocybin treatment of intractable depression.

Psilocybin is one of the psychoactive agents that triggers neuroplasticity, allowing the brain to make new adaptations.
 
JBR said:
There are research projects going on in four or five cities in the U.S., aimed at establishing psilocybin's usefulness in treating emotional issues, such as PTSD and depression. England has pursued this, possibly for longer than the projects n the U.S. For several years now, Canada has had a cross-country project for psilocybin treatment of intractable depression.

Psilocybin is one of the psychoactive agents that triggers neuroplasticity, allowing the brain to make new adaptations.
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Yes. Sounds silly but the only thing that's held US scientists back is a law passed over 40 years ago; in 1965, I think. A law that strictly prohibits the possession and use of LSD and any derivative of psilocybin, in any way, and any form, for any reason.

Scientists don't know why this law has "remained on the books" for over 40 years. Especially since US psychotherapists have been buying it from Canada and Mexico and treating their patients with it (mainly war veterans) for at least a couple decades.
 
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Murrmurr said:
It will be considered a controlled substance, according to the FDA.

In conjunction with research, some universities and general laboratories will be adjusting/rearranging its molecular structure for the purposes of medical treatment for both physical and mental health problems, and I imagine Big Pharma will also. I'm sure this will include reducing the hallucinogenic properties, but I don't doubt law enforcement will have to come up with a low-range for impaired driver, right?

That will probably be FDA recommended. I believe that's the case with Rx opioids. I take a prescribed opioid, but I can be charged with a DUI if I'm involved in a fender-bender or something and test above whatever the Calif limit is. Doesn't matter that it's prescribed.

I bet the only way to measure that will be a blood test...that presents a problem.
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I'm sorry but, I'd rather they just leave it as a natural substance. If you get Big Pharma involved - defeats the purpose. All they do is keep us sick!

I've read a lot about the benefits of micro dosing -where there is NO psychedelic effects. That's what I would be interested in ... pure, natural and very low dose.

Forgive me, I've lost about all respect and faith in most of those lettered agencies. I think I'm getting a bit cynical in my old age. :)
 
CaliS said:
I'm sorry but, I'd rather they just leave it as a natural substance.
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But different elements within its molecular structure provide different benefits. Researchers want to isolate those elements, which will maximize their properties and (ergo) the effectiveness of the resulting medications.

Scientists are hoping to create 3 classifications of medications, at least to start with. And they're already looking at a possible 4th classification (treatment for age-related mental decline).
 
Murrmurr said:
But different elements within its molecular structure provide different benefits. Researchers want to isolate those elements, which will maximize their properties and (ergo) the effectiveness of the resulting medications.

Scientists are hoping to create 3 classifications of medications, at least to start with. And they're already looking at a possible 4th classification (treatment for age-related mental decline).
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I hope they are successful and left to do what benefits people. :)
 
CaliS said:
I hope they are successful and left to do what benefits people. :)
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I agree with you that Big Pharma realizes massive profits by keeping people sick. A couple tactics Congress can use are, either greatly incentivize Big Phat Pharma to research and develop actual cures while also reducing or even halting funds for developing treatments, particularly ones with known harmful side effects, OR simply invest big bucks in a few smaller pharmaceutical labs so they can work on actual cures.

Yeah, we have to eliminate the H&H Gravy train-stop at Big Pharma. That destination doesn't even make sense anymore.
 
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