Actually, the Airbus has a very good safety record, along with Boeing. Lockheed ran into problems with some of their Constellations. The L-1011 built by Lockheed was another plane thought to be indestructible, but the Delta crash in the Everglades wiped out any thoughts about that. Lockheed also had a mess of problems with trying to defraud the gov't with billing costs. The Airbus A-380 is a huge plane and although I have never flown in it or flown it as a pilot, I would highly recommend it. (I have toured it on the ground.) It has a truckload of safety sensors that even the sensors have sensors and that's not a play on words, but truthful. Just like airplanes have a back-up system for every mechanical and electrical system, the Airbus A-380 has a back-up sensor for each sensor. It's amazing.
I have always been a Boeing man. It's like Ford and Chevy. you either like one or the other. The Boeing 787 Dreamliner is a superb piece of machinery and is the competitor to the Airbus A-380. I have personally held ratings for the Boeing 737, 747, 757 and 767. The B-747 has the best safety record in the business as far as jumbo jets go. As for engines, between the Rolls Royce, GE and Pratt & Whitney, I prefer them just in that order. The RR engines seem to run cooler and give off fewer alarms, according to ALPA, which is the pilot's main go to reference on such things. A few years before I retired, I flew a B-767 with two brand new replacement Rolls Royce engines. I noticed how quiet they ran and how quick they were able to accelerate. Of course, price is always a concern to airlines, so most B-767's are equipped with P&W engines, but still are very safe.