Trust, but Verify

Tom Young

Member
Location
Illinois/Florida
Experimenting with drugs

Upfront... sounds like an introduction to today's funniest comments, but......

Totally serious, and for DW and me, actions that have helped us, and we think, may be extending our livespan.

Sometime ago, I had written here that we listened to our doctor, and didn't second guess her recommendations for pharmaceuticals, except to request generics. That's true... but there's a second part of this, and that is we watch our health, and do some experimenting with dosages. In most cases, it's a matter of balancing health and side effects.

To begin, since it's usually a one time thing, we read as much as we can on the WebMD and similar website about the interactions, side effects, dosage amounts, warnings etc. More practical than the fine print fact sheets that accompany the prescriptions.

After that, we take the medicine as recommended, and consciously watch for side affects... sleep, intestinal problems, nervousness, whatever was part of the "possibles".
.................................................
Next, instead of tryingto explain, some experiments, and what we did to improve.

Frist, was Lipitor... started when it was introduced, and it did drop the cholesterol readings, successfully... Kudo's to the Doctor. Some four years later, with tweaks in the arm, thought to be from tennis injury, then some aching in the legs, Doctor diagnosed arthritis, and prescribed Celebrex. It helped. (this was before Lipitor and muscle weakness reached the news)...
The price of Celebrex seemed high, so turned to aspirin, but with more tummy problems... Finally decided to stop lipitor... an experiment. In two weeks, leg and arm pain went away. Doctor recommended Simvastatins, and that worked pretty well... but Triglycerides were still very high... 700+... Went to Crestor, that helped, but still expensive. We changed doctors because of moving. New doctor prescribed fenofibrate (generic) and that worked for aches, cholesterol and triglycerides, plus reasonble cost.

Next, borderline diabetes... Dr. prescribed Metformin, diagnosing metabolic syndrome. Took the pills for a year, then after a summer of moderate exercise, lost about 7 pounds. Went off the metformin at camp, when I ran out of pills for a week. At a mall health clinic, had a free blood test with result of 74... below the 114. So much for metformin... wouldn't have known, except for that test. Blood sugar, now fine.

Then... DW... several different situations, now all under control, but a few interesting experiments.

An accidental experiment for me... At the time, she had been taking clonazepam for another reason... I had begun to have sleep problems... down to 2 or three hours/night. Doctor prescribed the OTC Benadryl first, which just made me dopey, but with very restless sleep. Changed to Ambien... For me awful... sleep, but with continuous nightmares and terrors. Then (I wouldn't usually do this, but tried DW's clonazepam, and slept like a baby. Worried about addiction, tlked to Dr. and she rhetoriacally asked me... "how old are you"... and when I told her, she laughed and said "... and you're worried about addiction?" So now, have the prescription... .25 mg to.50mg/night and life is good.

DW takes BP Amlodipine, and gets "good show" at Dr. office for BP in the 110/65 range... Trouble is, she has had some dizzy spells, when getting up from a chair or rapid movement... We have a home BP machine so started monitoring regularly... sometimes, as low as 95/50. This time, we did it on our own... cut pill in half, and watchfully see BP up into the 120 to 130/75 range... low for our age, but a little higher that what the office praised her for. The good part... dizzy spells are gone, and more energy.

One more... Two years ago, after having hand "pins and needles" and some pain especially at night, a doctor... neuropathy... diagnosed as carpal tunnel. An operation... $12K... but no relief... sent to a neuropathy specialist who wanted to do a huge battery of tests, but when pressed for expectations was non commital. I did some very extensive reading about the problem, and came to the conclusion that it was peripheral neuropathy... with an almost zero chance of improvement... OLD AGE... Coming to grips with that, life has normalized... and in the way people with permanent disabilities deal with them, have made it a tiny part of my life. Don't even notice it any more. Have a prescription for nerve pain, ... gabapentim, but harldly ever use it.

Over the years, we've had many more self diagnosis/medication situations, but not necessary to list here. Here's the point of the post... As we look around us at people who are as old and older than us, we see many who are taking as many as 15 different pills/day. Not for us to say whether they are needed or not. Most of them trust their doctors, and credit medication with keeping them alive. At the same time, I do not and could not criticize the doctors, as their prescriptions are based on blood tests, and the symptoms that present. Also, I would guess, more likely to add a prescription and watch the results, than to take away and see more problems or death.

For us, it takes some effort to read about and understand our personal health, but we feel it's worth the extra effort. didn't intend this to be so long, but sometimes personal experiences mean more than long narratives. I believe that sharing, helps in understanding.
As always, my opinion only... YMMV
 

I'm interested in Lipitor and muscle weakness and arthritis.
I'm on Lorstat, a generic of Lipitor I believe, and I'm having a lot of trouble with my legs and now my shoulders.
I'm due to see the heart specialist soon so I'll mention it and see what he says.

Thanks, Tom, for this post.
 
Hooray.....somebody who intelligently enquires and tests their medication!

You control your medication; it does not control you; and an intelligent dialogue with your doctor/pharmacist can avoid many problems.
 

... and an intelligent dialogue with your doctor/pharmacist can avoid many problems.

This is something that I do not understand, Viv - perhaps you could enlighten me ...

My private student is a long-time pharmacist - used to own his own franchise but burned out after 25 years or so. He now works "part-time" (30-35 hrs / wk) at another pharmacy - from the same franchise - as "just a pharmacist".

He regularly tells me of people coming into the shop and asking him questions that, in my opinion anyway, would be far more appropriate - and legal - to ask their doctor.

Now, I understand that the issue is often one of time and convenience - it's tough to schedule a doctor's visit and they aren't a captive audience like my student - so they'll come in and relate their medical history and ask for treatment advice.

My student, while trying to be helpful, is ever-mindful of the law and thus has to walk a fine line.

Basically, I see a broken system when a patient is asking their pharmacist for medical advice and only go to their physician for prescriptions.
 
I,too,had nothing but problems with any of the statins. Leg pain and shoulder pain on Lipitor,Crestor,Simvistatin and another that I have forgotten the name of. Doctor took me off and within a week my pain was gone. Since that time,I`ve heard some negative things about statins,whereas ten years ago my doc told me that cardiologists had once told her that they were the greatest med ever invented and that pretty much everyone should be taking them. But for me,the pain was just too much to deal with.
 
The fact is in 2012 the FDA contacted doctors and told them to get their patience off statins as they cause 52% chance of diabetes and 100% chance of dementia [Alzheimer] I guess your doctor was too busy to tell you.
 
I have made the decision to wean myself off the tablets my neurologist has put me on due to the fact that the MRI & Doppler were normal, i refuse to keep taking tablets that basically stop seizures but also work on nerves when all they do is make me feel like a zombie and want to sleep all day, i have put up with the pain for 21/2 years so i can put up with it for however long it is giving me grief and just take pain killers when it's really bad.
The doctors put me on Simvastatin years ago and i was always itchy so went off them and they have been trying to get me on them ever since, i refuse to take them, there are natural ways of reducing the cholesterol like Aloe vera or Beetroot juice
 
Unless your cholesterol is over 270 than you have no problem the naturopath doctors say good cholesterol range is from 220 - 270
 
Phil; yes there is a fine line...
Over here; pharmacists dispense medicines prescribed by a doctor.
under that heading comes giving advice over side-effects; when best to take them; any interactions with other medicines they are taking; when and whether to stop taking them; what they are used for (yes!) and any other questions about compliance etc.
also, when to return to the doctors if necessary, and how to tell if they are doing what the patient wants them to, and what the doctor expects.

We also trat a lot of self-limiting conditions...fungal infections of skin and nails; mild to moderate pain; and all types of illnesses which you have ever heard of, and some you haven't!

We are supposed to use our professional judgement about what we can treat, and what people have to attend their doctors for.

Doctors are ok at diagnosing, and choosing the medicine that in theory works.

Pharmacists tend to do all the practical stuff; including checking the script is legal, and many interactions.

Because the NHS is free at the point of delivery; many pain-killers, and creams etc available OTC are not allowed on prescription; I expect that doesn't happen in the US.

Also, we don't have an appointment system; in some places people have to wait 2weeks to see their GP; which would you prefer; a pharmacist or a doctror's receptionist?!
 
Phil; yes there is a fine line...
Over here; pharmacists dispense medicines prescribed by a doctor.
under that heading comes giving advice over side-effects; when best to take them; any interactions with other medicines they are taking; when and whether to stop taking them; what they are used for (yes!) and any other questions about compliance etc.
also, when to return to the doctors if necessary, and how to tell if they are doing what the patient wants them to, and what the doctor expects.

"When and whether to stop taking them" - see, in my mind that's the physician's responsibility, because it's getting into actual treatment protocol. Again, I'm just an outsider and going by what my student says.

We also trat a lot of self-limiting conditions...fungal infections of skin and nails; mild to moderate pain; and all types of illnesses which you have ever heard of, and some you haven't!

We are supposed to use our professional judgement about what we can treat, and what people have to attend their doctors for.

Doctors are ok at diagnosing, and choosing the medicine that in theory works.

Pharmacists tend to do all the practical stuff; including checking the script is legal, and many interactions.

I get the impression that pharmacists work a LOT harder than most doctors.

Because the NHS is free at the point of delivery; many pain-killers, and creams etc available OTC are not allowed on prescription; I expect that doesn't happen in the US.

I'm not quite sure how that would work here, either - I'll have to find out.

Also, we don't have an appointment system; in some places people have to wait 2weeks to see their GP; which would you prefer; a pharmacist or a doctror's receptionist?!

Certainly the shorter time period, UNLESS the problem I had was more properly treated by a GP. See, that's the thing I'm concerned about - pharmacists being used as doctors. I could foresee a lot of lawsuits coming up if you aren't careful ...

This is all just academic for me, by the way, since I don't take pills or visit either doctors or pharmacists. ;)
 
"This is all just academic for me, by the way, since I don't take pills or visit either doctors or pharmacists."

Bless you... academia forever!
:)
...........................................................................................

Back to Cholesterol etc... and the doctor visit...
Based on age, higher readings for cholesterol, tryglycerides, PSA and blood pressure are more commonly accepted as "normal".
In my case original LDL was over 350, and tryglycerides 1000 at one point. Even now, with medication, levels are in the high range, but the doctor seems to consider that ok, considering past history.
Have learned to understand blood tests, and always ask for a copy of the reults after annual physical.


One more small point. Before we go to for a physical, we always spend some time, questioning each other (bride and self) about those little things that have bothered us during the past year... even if they don't seem too important. I make a list of the questions we need to ask... things that we used to ignore or forget about some years ago. Always have blood tests before the Dr. visit.


We are very, very happy with our young 36 y.o. female doctor. She's up on the latest medicine, and if there's ANY question, instead of showing off her knowledge, she'll take a break and look up anything that she's not positive about. She has attained sainthood (for us) by spending an hour or more checking through every health item possible, and never letting us go with any kind of a question unanswered. We have never had a better doctor, or felt such confidence. (she's very personable, and calls me "Dr. Bob".)
 
Hi Vivjen.. Have you heard in UK that hydrochlorothiazide.used in blood pressure medications causing nerve damage and pains in legs..
I for one seem to think it does... and I feel its what has been making my legs worse and weakening?.. I take avapro with hydrochlorothiazide .
also my husband was on Liptor for over 20 yrs he developed hip and leg pains and shoulder pains.. he went to a new doctor who was from
Yorkshire.. he said to my husband why are you taking 80mg of this medication.. in UK it is only allowed to be 40mg whereas he changed it down..
my husbands has had no change in his cholesterol and blood pressure normal but the pains are gone.. so he never needed the other 40 mg in the first place..
do you also know about the drug alpha lipoic acid ? I think it can be bought over the counter and it helps peripheral nerve pains. do you know if its true?
thanks so much if you can answer this ... it means a lot to me..
 
Hi Rainee,
hydrochlorthiazide is not used a lot in UK any more; especially in a combination; because of problems and side effects it causes.

There is now a 4 step algorithm for hypertension..and hydrochlorthiazide is introduced in step 2 with an ace-inhibitor, but you can use something else instead.
it may be worth seeing if irbesartan on its own does the trick; because you can upset your electrolyte levels.
 
I would agree with Lipitor....20mg is the most widespread dose over here; 80mg hardly ever used!

Will deal with your last question later; a little conversion is required from my end...but I won't forget!
 
I have decided it will be safe enough to conduct a little experiment.

I've decided to discontinue taking my Lorstat (Lipitor by another name?) for two weeks.
I will continue with the Panadol Osteo for one week then discontinue that too for the second week.

So far I've missed two cholesterol tablets and already my legs/knee are feeling brand new, I can rise from a chair with relative ease and I'm walking rather than shuffling. I'm amazed at the difference and I will certainly be talking to my doctors about this medication.
 
... I'm amazed at the difference and I will certainly be talking to my doctors about this medication.

Congratulations.

I think talking to your doctors about this will be preaching to a deaf choir - you can't talk a pill-pusher into giving up their business when it earns them so much money.
 
I disagree Phil; but mainly because the healthcare systems are so different.

I would go with Warrigal all the way....and I know my doctor would agree..
 
Nothing to forgive; I just don't understand the healthcare system in US; our doctors make no money from their scripts ; so financial inducements are completely different?
 
I know several people who take statins to treat cholesterol. It works well for them without side effects. I'm not so lucky.
Whenever I've taken statins, I have difficulty walking. Also (while on lipitor) my kidneys began to shut down.
The doctor took me off statins immediately. He said there was so much dead muscle tissue in my system it overloaded my kidneys.
I can't take ANY statins. They all have similar ingredients and tear up my muscles.
The doctor told me we must remember that the heart is a muscle and the statins could damage it.
I've had one heart attack (before I ever went on statins) and certainly don't want to do further damage.

My point - If you have muscle weakness while taking statins STOP TAKING THEM!!!!
Your heart is a muscle!
 
About seven years ago I stopped taking Pravastatin/pravacol as it was starting to affect my wellbeing with pains in the kidney area and also muscle pain, I weaned myself off them gradually and have felt much better for doing so, I also stopped taking blood pressure meds for high blood pressure at the same time,now my blood pressure is below what it should be and I don't understand why I was put on them in he first place, I think too many Drs only take your pressure once and it shows up high so they then put you on meds when maybe they are not needed.
Here is a good link to see what Statins can do to you http://spacedoc.com/statin_side_effects
 
Nothing to forgive; I just don't understand the healthcare system in US; our doctors make no money from their scripts ; so financial inducements are completely different?

The U.S. medical profession has a long history of being the whipping boy of the pharmaceutical industry. In the '50's and '60's physicians would receive extravagant gifts, including sums of cash, to carry a specific pharmaceutical. They were basically being rewarded for being bird-dogs.

After a ruckus was raised over this practice, it went underground. Now, you cannot be a practicing physician for very long if you don't carry what your "masters" (the insurance companies) tell you to carry. So no, physicians are no longer rewarded for prescribing their drugs - now they are threatened if they do not.

From positive reinforcement to negative, all in the course of a few decades.
 
Congratulations.

I think talking to your doctors about this will be preaching to a deaf choir - you can't talk a pill-pusher into giving up their business when it earns them so much money.
Until my light bulb moment caused by this thread I was ready to talk to my heart specialist about whether my heart is OK for an operation on my knees but now I'm going to question him as to the desirability of continuing medication originally prescribed 3-4 years ago that now seems to be adversely impacting my quality of life.

I don't think it will be a pointless conversation and I am confident that my own GP will be receptive to my reporting that I do seem to be experiencing undesirable side effects. He has examined my knee X-rays and my knees are not that bad that an operation is warranted at this stage but I have been becoming less and less mobile over time. However, after skipping three doses of my cholesterol medication, I've been rejuvenated.

I am quite astonished by the difference.
 


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