The flip side: I had a terrible poison ivy reaction (occupational hazard). I needed a huge shot of anti-histamine. The doc asked me if I had a long way to drive home. I told him I lived ten minutes away. On the way home, I slowwwwwwed down. Hit the sack at noon, awoke 2 PM, the next day. Cats and dog were pretty angry at me. I felt great, though, and the rash was completely gone