I take a daily "Men's over 50" multivitamin, and a fish oil capsule and a 6mg. Lutein pill every morning. The vitamin gives me the daily recommended dosages, in case I don't eat right, and the fish oil/Lutein is per my eye doctor as a means of staving off Macular Degeneration...which my old Dad had.
When I go in for my annual checkups, everything seems ok....so I plan on keeping this regimen going. I take NO prescriptions, and only keep a small bottle of generic Aleve pills around in case I overwork my slight arthritis...I might take one of those every couple of weeks.
Finding the right "supplements" can be a bit tricky....everyone is different....but, if you can find something that works, a few pennies a day is some pretty cheap health insurance.
Insofar as "weight loss" is concerned, I doubt there is any Magic Pill for that....it almost always boils down to Diet and Exercise.